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Drug Synergism and DoseEffect Data Analysis

Not since this author''s bestselling Manual of Pharmacologic Calculation-long out of print-has there been a reference available for drug data analysis, and even that work did not deal with drug combinations. Although pharmacologists and most other scientists know what synergism is, mainstream textbooks tend to neglect it as a quantitative topic. Few researchers are familiar with the quantitative methodology needed to differentiate synergistic responses from the simply additive responses expected from drug combinations or a single drug''s interaction with endogenous chemicals.In Drug Synergism and Dose-Effect Data Analysis, noted pharmacologist, mathematician, and author Ronald J. Tallarida finally brings these methods to light. Drawing on statistical theory and methods but keeping the spec